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sage decreases results of diazepam by pharmacodynamic antagonism. Minor/Importance Unidentified. Theoretical interaction; some species of sage may possibly lead to convulsions.
fentanyl intranasal and diazepam both improve sedation. Keep away from or Use Alternate Drug. Restrict use to patients for whom option cure choices are inadequate
May harm an unborn child. Do not use if you are Expecting or may perhaps turn into Expecting. If you use diazepam in the course of pregnancy, your little one could possibly be born with life-threatening withdrawal signs and symptoms, and might require medical procedure for quite a few weeks.
When you are using a seizure, Additionally they need to have to find out how long to wait before giving you rectal diazepam. This depends on the type of seizure and how long it lasts.
sparsentan will reduce the extent or effect of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Use Caution/Monitor. Sparsentan (a CYP2C19 inducer) decreases publicity of CYP2C19 substrates and minimizes efficacy associated with these substrates.
diltiazem will boost the stage or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
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In case you are Expecting, your title can be listed with a pregnancy registry to track the results of diazepam on the child.
Can I consider diazepam before surgical procedures? Diazepam could be specified as being a pre-med to relax you right before an Procedure or dental treatment method Which may be awkward or make you feel nervous.
Reserve concomitant prescribing of such prescription drugs in patients for whom other cure solutions are inadequate. read more Restrict dosages and durations into the bare minimum necessary. Keep track of closely for signs of respiratory despair and sedation.
fentanyl transmucosal and diazepam equally maximize sedation. Avoid or Use Alternate Drug. Limit use to patients for whom different therapy solutions are insufficient
The above information is furnished for typical informational and academic functions only. Particular person programs may fluctuate and formulary information and facts adjustments. Get in touch with the applicable approach company for essentially the most present-day details.
diazepam will improve the level or impact of midazolam intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Coadministration of gentle CYP3A4 inhibitors with midazolam intranasal might cause bigger midazolam systemic exposure, which can prolong sedation.
drospirenone will raise the stage or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unfamiliar.